FIELD: medicine.
SUBSTANCE: group of inventions also relates to a microparticle composition containing sialidase fusion protein obtained by a method comprising addition of a counterion selected from sodium citrate, sodium sulfate, calcium sulfate, potassium sulfate and magnesium sulfate to an aqueous solution containing the fusion protein, addition of an organic solvent, selected from methanol, ethanol, 1-propanol, isopropanol, tert-butyl alcohol and butanol, to this solution and gradually cooling of the solution to a temperature below 25°C; and relates to a method for influenza or parainfluenza treatment comprising administration of the said compositions to the patient.
EFFECT: group of inventions provides effective active agent delivery to the respiratory tract and long-term stability.
35 cl, 12 tbl, 12 ex
