FIELD: chemistry.
SUBSTANCE: invention relates to a method for producing 1H-benzo[ƒ]chromen-2-yl(aryl)ketones by the reaction of substituted 1-[(dimethylamino)methyl]-2-naphthols with 3-(dimethylamino)-1-aryl-prop-2-ene-1-ones. Obtained compounds are advanced parent compound for the purpose of the synthesis of pharmacologically active substances. The method is carried out by using available 3-(dimethylamino)-1-aryl-prop-2-ene-1-ones and acetic acid without the need to use an inert atmosphere and catalysts.
EFFECT: simplified technological process and cheaper production.
14 ex
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Authors
Dates
2017-10-12—Published
2015-12-04—Filed