FIELD: chemistry.
SUBSTANCE: invention relates to method of producing 4-aryl-2-oxo-2H-chromen-3-carbonitriles of general formula, wherein R1=C6H5, 3-NO2C6H4, 4-H3COC6H4, R2=OH, R3=R4=R5=H; R2+R3=-CH=CH-CH=CH-, R4=R5=H; R2=R3=H, R4+R5=-CH=CH-CH=CH-, which consists in fact that corresponding 4-aryl-4H-chromen-2-amine is oxidised on silica gel by heating at temperature of 100-150°C with air flow for 24 hours, after which obtained end product is separated by extraction with ethyl acetate.
EFFECT: these compounds can be used as biologically active compounds, specifically compounds possessing anticancer, antimicrobial, antiviral activity, antioxidant properties.
1 cl, 6 ex
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