METHOD OF DIFFERENTIAL DIAGNOSTICS OF MAMMARY GLAND AND SOFT TISSUE GROWTHS Russian patent published in 2017 - IPC A61B8/08 A61B8/06 

FIELD: medicine.

SUBSTANCE: ultrasound is performed with intravenous contrast enhancement using the high resolution mode, the microbubble tracing mode MTI, the MI mechanical index value equal to 0.06, with the focus setting under the growth. The vascularization and perfusion of the growth are evaluated using kinetic curves and contrasting patterns. There are kinetic curves of I, II, III types and the following contrasting patterns - annular, annular with the parietal component, dendritic, spicular, spiral, wherein: I type of kinetic curve - gradual linear increase in contrast enhancement of the growth during the study, II type - linear increase in contrast enhancement of the growth with the subsequent plateau phase, III type - peak of the contrast enhancement of the growth, which occurs at the first seconds, then a rapid subsequent decrease in the enhancement. The annular pattern - the vascular neoplasm pattern resembles a ring, is characterized by single microvessels with the same diametre and uniform distribution along the periphery of the growth, the annular pattern with the parietal component - the vascular pattern resembles a ring with the parietal component, is characterized by single microvessels along the periphery of the growth and uneven parietal distribution, the dendritic pattern - the vascular pattern resembles twigs of a tree, is characterized by multiple microvessels with the same diametre and uniform distribution in the structure of the growth, the spicular pattern is characterized by multiple microvessels along the periphery of the growth, which have a chaotic, spicular distribution; the spiral pattern - the vascular pattern resembels spirals with different diametres, is characterized by multiple microvessels with different diametre and uneven asymmetrical distribution. When visualizing the annular pattern or dendritic pattern in combination with a kinetic curve of types I or II or the annular pattern with a parietal component in combination with a kinetic curve of I type, a benign growth is diagnosed. When visualizing the annular pattern with the parietal component, or the spicular pattern, or the spiral pattern, in combination with the kinetic curve of III type, malignant growth is diagnosed.

EFFECT: increased accuracy of differential diagnostics of mammary and soft tissue growths by creating new evaluation criteria of vascularization and perfusion of growth using kinetic curves of enhancement-time and contrasting patterns.

17 dwg, 2 tbl, 4 ex