METHOD FOR PREVENTION OF AGITATION SYNDROME IN CHILDREN WITH ONCOLOGICAL PATHOLOGY Russian patent published in 2017 - IPC A61K31/4402 A61K31/415 A61P23/00 

Abstract RU 2635532 C1

FIELD: medicine.

SUBSTANCE: methodincludes single intranasal injection of dexmedetomidine at a dose of 2 mcg/kg prior to anesthesia with sevoflurane on a semi-open contour with maintained spontaneous breathing. Application of the invention makes it possible to achieve pre-anesthesia sedation level R3-R5 on the Ramsey scale without respiratory depression, development of analgesic effect.

EFFECT: decrease in MAC of sevoflurane, prolongation of postnarvic sleep, a decrease in intracranial pressure, level of cerebral blood flow, and brain oxygen consumption.

2 tbl, 2 ex

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RU 2 635 532 C1

Authors

Tumanyan Sergej Vartanovich

Semiletkina Elena Yurevna

Kuznetsov Sergej Alekseevich

Dates

2017-11-13Published

2016-09-06Filed