FIELD: biotechnology.
SUBSTANCE: chimeric fusion protein containing a targeting moiety for cancer cell targeting, an immunomodulating moiety that counteracts the immune tolerance of cancer cells, and an amino acid spacer is prepared recombinantly.
EFFECT: invention allows to increase the effectiveness of cancer diseases treatment.
9 cl, 65 dwg, 1 tbl, 12 ex
| Title |
Year |
Author |
Number |
| FUSED IMMUNOMODULATORY PROTEINS AND METHODS FOR PRODUCTION THEREOF |
2014 |
- Govindappa Nagaraj
- Soares Maria Melina
- Sastry Kedarnath
|
RU2698975C2 |
| FUSION IMMUNOMODULATORY PROTEINS AND METHODS FOR MAKING SAME |
2014 |
- Govindappa Nagaraj
- Soares Maria Melina
- Sastry Kedarnath
|
RU2662991C2 |
| VACCINE COMPOSITION AND USE THEREOF |
2016 |
|
RU2726411C2 |
| HER-2-DIRECTED ANTIGEN-BINDING MOLECULES CONTAINING 4-1BBL |
2019 |
- Ferrara Koller Claudia
- Iuntilla Teemu Tapani
- Klein Christian
- Umana Pablo
- Claus Christiana
|
RU2815451C2 |
| COMBINATION OF AN IMMUNE CHECKPOINT MODULATOR AND A COMPLEX CONTAINING A CELL-PENETRATING PEPTIDE, A CARGO MOLECULE, AND A TLR PEPTIDE AGONIST, FOR APPLICATION IN MEDICINE |
2017 |
- Derouazi Madiha
- Belnoue Elodie
|
RU2769314C1 |
| BISPECIFIC BINDING MOLECULES CAPABLE OF BINDING CD137 AND TUMOR ANTIGENS AND VARIANTS OF THEIR APPLICATION |
2018 |
- Lyu, Litsin
- Lam, Chia-In Kao
- Didrikh, Gundo
- Dzhonson, Lesli S.
- Mur, Pol A.
- Bonvini, Etsio
|
RU2805648C2 |
| FUSED POLYPEPTIDE WITH ANTICANCER ACTIVITY |
2016 |
- Hinner Marlon
- Rothe Christine
- Olwill Shane
- Bel Aiba Rachida Siham
- Moebius Ulrich
- Schlosser Corinna
- Jaquin Thomas Jean
|
RU2727165C2 |
| COMBINATION OF IMMUNE CHECKPOINT MODULATOR AND COMPLEX CONTAINING CELL-PENETRATING PEPTIDE, CARGO MOLECULE, AND TLR PEPTIDE AGONIST FOR MEDICAL USE |
2017 |
- Deruazi Madikha
- Belnu Elodi
|
RU2748378C2 |
| NK-CELL ACTIVATING FUSED PROTEIN, NK-CELLS AND A PHARMACEUTICAL COMPOSITION CONTAINING THEM |
2018 |
- Kim, Seok Ho
- Lee, Jaemin
- Cho, Duck
|
RU2740438C1 |
| BISPECIFIC BINDING AGENTS WITH INTERSPECIFIC SPECIFICITY |
2008 |
- Klinger,Matthias
- Raum,Tobias
- Rau,Doris
- Mangold,Susanne
- Kischel,Roman
- Lutterbuse,Ralf
- Hoffmann,Patrick
- Kufer,Peter
|
RU2535992C2 |
