FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to field of biotechnology and microbiology. Claimed are vaccine against necrobacteriosis and method for obtaining thereof. The vaccine contains formalin-inactivated leukocidin - exotoxin, obtained from Fusobacterium necrophorum, adsorbed on aluminium hydroxide, and additionally saponin, glycerin at a definite ratio of components. Leukocidin, included into the vaccine composition, is the exotoxin, obtained from industrial strain Fusobacterium necrophorum "0-1" VIEV, and represents highly purified protein with molecular weight 18-20 kDa with content of 1.5-2.0 billion of Fusobacterium necrophorum "0-1" VIEV cells per 1 cm3.
EFFECT: claimed vaccine can be used in veterinary to prevent necrobacteriosis in animals.
2 cl, 5 dwg, 2 ex
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