FIELD: veterinary biotechnology. SUBSTANCE: serum contains antibodies to Fusobacterium necrophorum in a titer being not lower than 1:128 in reaction of agglutination (RA). It is obtained by hyperimmunization of producer bullocks with inactivated formalin leucocydine-exotoxin. The latter is a highly purified protein at 18-20 kDa molecular weight isolated from a production strain Fusobacterium necrophorum "0- 1" VIEV. Hyperimmune serum provides the development of tense passive immunity against necrobacteriosis in cattle and reindeers in case of single injection for about 14 d, not less Therapy efficiency corresponds to 90%. EFFECT: higher efficiency. 2 ex, 1 tbl
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