FIELD: medicine.
SUBSTANCE: invention can be used to detect an antibody in a test sample containing the body fluid of a mammalian subject. The antibody is directed to a foreign antigen introduced into the said mammalian subject. The method comprises the steps of: (a) test sample bringing into contact with a plurality of different amounts of the antigen specific for the antibody, (b) detection of specific binding of the said antibody and the said antigen of step (a), and (c) plotting or calculation of a dependency curve for the said specific binding value and the amount of antigen for each amount of antigen used in step (a). The presence of the antibody in the test sample is indicated mainly by an S-shaped or sigmoid curve.
EFFECT: detection of antibodies as biological markers of a disease state or a predisposition to the disease.
10 cl, 15 dwg, 6 tbl, 7 ex
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| METHOD FOR MEASUREMENT OF ANTIBODIES TO WT1 | 2012 |
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| IMMUNOLOGICAL TEST FOR DETERMINING AUTOANTIBODIES AGAINST TESTICULAR ANTIGENS | 2009 |
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