DEVICE FOR NONINVASIVE MEASUREMENT OF BLOOD MICROSCIRCULATION FLOW Russian patent published in 2017 - IPC A61B5/26 

FIELD: medicine.

SUBSTANCE: device for non-invasive measurement of microcirculation flow in tissue contains a radiation source (2) to illuminate the biological tissue under study (12), a photodetector (3) to record radiation scattered back from the issue, an electronic filtering unit for the registered signal (4), a background noise subtraction unit (7), a unit for determining and indication of the perfusion index of the tissue under investigation (10), and a control and synchronization unit (11). The electronic filtering unit comprises an analog-to-digital converter (5) and a digital signal averaging unit (6) to average the useful signal with a background noise signal and average the background noise signal from the measured signal values, respectively. The background noise subtraction unit comprises an on-line memory (8) to store the calculated average values of the background noise signal and the total signal respectively, and a difference unit (9) to subtract the average background noise signal from the average total signal. The perfusion value determination and indication unit is configured to calculate a perfusion index based on the useful signal of the first moment of the useful signal spectral power density normalized by the constant component and to display the indicated value. The control and synchronization unit is configured to generate rectangular control pulses with a duty cycle of 50%. The radiation source is made in the form of at least three IR diodes emitting in the wavelength range of 800-820 nm, located at an equal distance from each other radially around the photodetector and flush with the working surface of the photodetector.

EFFECT: increased accuracy of the device by subtracting background noise, increasing its noise immunity and safety by using LED radiation sources instead of lasers without application of optical fibers.

4 cl, 5 dwg