FIELD: medicine.
SUBSTANCE: TGF-β antagonist is introduced, which is an antibody containing the VH-domain of PET1073G12 (SEQ ID NO: 2) and the VL-domain of PET1073G12 (SEQ ID NO: 7). Introduction is carried out within 72 hours from the onset of myocardial ischemia.
EFFECT: reduced fibrosis, improved remodeling and myocardial function.
20 cl, 2 tbl, 30 dwg, 6 ex
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Authors
Dates
2017-11-29—Published
2011-09-01—Filed