MYOCARDIAL INFARCTION TREATMENT USING TGF-BETA ANTAGONISTS Russian patent published in 2017 - IPC A61K39/395 A61P9/10 

Abstract RU 2637088 C2

FIELD: medicine.

SUBSTANCE: TGF-β antagonist is introduced, which is an antibody containing the VH-domain of PET1073G12 (SEQ ID NO: 2) and the VL-domain of PET1073G12 (SEQ ID NO: 7). Introduction is carried out within 72 hours from the onset of myocardial ischemia.

EFFECT: reduced fibrosis, improved remodeling and myocardial function.

20 cl, 2 tbl, 30 dwg, 6 ex

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RU 2 637 088 C2

Authors

Akita Dzheffri I.

Lonning Skot

Gregori Richard K. Ml.

Kudej Ameliya B.

Dates

2017-11-29Published

2011-09-01Filed