FIELD: pharmacology.
SUBSTANCE: invention relates to compounds of the general formula (I)
,
where R1 and R2 are different or identical and are independently selected from the group consisting of: - H; -(C1-C6)haloalkyl; -(C1-C6)alkyl optionally substituted by one or more substituents selected from (C3-C7)cycloalkyl; and -(C3-C7)cycloalkyl; A is a monocyclic heteroaryl ring system selected from the group consisting of radicals
, 
, 
, and 
,
n is 0, 1 or 2; R3 is a possible substituent, which in each case is selected from the group consisting of: -(C1-C6)alkyl, optionally substituted by (C3-C7)cycloalkyl; -OR4, (the meaning of the remaining radicals is given in claim 1), its corresponding N-oxide over the pyridine ring and pharmaceutically acceptable salts or solvates thereof. The compounds obtained are inhibitors of the phosphodiesterase 4 (PDE4) enzyme.
EFFECT: increased efficiency.
14 cl, 8 tbl, 19 ex
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