METHOD FOR DIAGNOSTICS OF INFLAMMATORY PROCESS IN LUNGS AND IN INTRATHORACIC LYMPH NODES IN PATIENTS WITH SARCOIDOSIS Russian patent published in 2017 - IPC A61B6/03 A61K51/00 A61M5/14 

FIELD: medicine.

SUBSTANCE: invention concerns determination of severity and prevalence of inflammation in lungs and intrathoracic lymph nodes (ITLN) in patients with sarcoidosis. Radiopharmpreparation (RPP) 99mTc-tehnetril is injected and x-ray study is carried out assessing the severity of RPP accumulation and its topical localization in the lungs and ITLN. At that, the RPP is obtained before the introduction, as follows: technetium-99m is injected into a vial with technetril lyophilisate after elution, placed in a lead container and heated on a water bath for 15 min since water boils at the level of the water in the bath above the level of solution in the vial, cooled to room temperature. After RPP introduction upon reaching its energy peak, gamma-scintigraphy and/or single-photon emission tomography of the lungs and ITLN is performed, defining the extent and prevalence of pathological process in the lungs and ITLN by calculation of RPP absorption index in the inflammation focus. Its value from 10% to 20% above the background values is considered normal - zero degree, from 21% to 30% - mild, from 31% to 40% - moderate, and over 41% - pronounced pathological inclusion of RPP.

EFFECT: method provides high safety and promptness of diagnosis, accuracy of expression and prevalence of the inflammatory process in the lungs and intrathoracic lymph nodes, irrespective of the radiographic data, an objective assessment of metabolic and inflammatory processes.

4 dwg, 1 ex