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(19)

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2 639 501

(13)

(51)

IPC

C12N15/62(2006-01-01)

C12N15/70(2006-01-01)

C12N1/21(2006-01-01)

C07K19/00(2006-01-01)

A61K47/42(2006-01-01)

C12N15/27(2006-01-01)

C12N15/31(2006-01-01)

C12N15/33(2006-01-01)

C12R1/19(2006-01-01)

(21) (22)

Application

2015146299, 2015-10-28

(24)

Start date

2015-10-28

(22)

Actual filing date

2015-10-28

(45)

Published

2017-12-21

(72)

Inventor

Slastnikova Tatyana AleksandrovnaUlasov Aleksej ValentinovichRozenkrants Andrej AleksandrovichUspenskaya Nataliya YakovlevnaSobolev Aleksandr Sergeevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Biologii Gena Rossijskoj Akademii Nauk

ESCHERICHIA COLI STRAIN - PRODUCER OF MODULAR NANOCONVEYOR FOR DELIVERY OF PHARMACEUTICAL AGENTS TO NUCLEI OF TARGET CELLS Russian patent published in 2017 - IPC C12N15/62 C12N15/70 C12N1/21 C07K19/00 A61K47/42 C12N15/27 C12N15/31 C12N15/33 C12R1/19

Abstract RU 2639501 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to E. coli Rosetta^TM strain (pRARE2, pR752), RNCIM B-11308. This strain is a producer of a modular nanoconveyor to increase the specificity and effectiveness of antitumor agents of 6His-HMP-NLS-DTox-(Gly-Ser)5-EGF. The present invention makes it possible to obtain a modular 6His-HMP-NLS-DTox-(Gly-Ser)5-EGF nanoconveyor.

EFFECT: increase in the specificity and effectiveness of antitumor agents.

2 dwg, 2 ex

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RU 2 639 501 C2

Authors

Slastnikova Tatyana Aleksandrovna

Ulasov Aleksej Valentinovich

Rozenkrants Andrej Aleksandrovich

Uspenskaya Nataliya Yakovlevna

Sobolev Aleksandr Sergeevich

Dates

2017-12-21—Published

2015-10-28—Filed