FIELD: chemistry.
SUBSTANCE: claimed sorption material contains a porous carrier, the functional groups on the surface of which are covalently bound to a ligand capable of forming strong complexes with bacterial endotoxins. The porous carrier is a pellet with a size of 50 to 900 microns, made of a polymer or a copolymer. The carrier is obtained on the basis of such monomers as acrylic acid, methacrylic acid, acrylamide, metakrilamid, methyl acrylate, methyl methacrylate, glicidil methacrylate, vinyl acetate, allilamin, sodium 2-metilprop-2-en-1-sulfonate, allylglycidyl ether, divinylbenzene, divinylbenzene, ethylene glycol, triethylene glycol dimetakrilat, N,N-bis (metakrilamid). The ligand for binding bacterial endotoxins is an amphiphilic organic compound containing primary and secondary amino groups and hydrophobic substituents. A method for the preparation of a new sorption material and its use for purifying an aqueous solution of protein or an aqueous saline solution or a solution of a blood plasma are proposed.
EFFECT: obtaining new selective sorbents for purification of liquid media from bacterial endotoxins.
3 cl, 2 tbl, 15 ex
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Authors
Dates
2018-01-23—Published
2016-12-21—Filed