FIELD: medicine.
SUBSTANCE: invention relates to production of sorbents used for medical purposes, namely for extracorporeal therapy of the patients with sepsis with the use of biological liquids sorption. Obtained sorbent is characterized by improved properties of covalently immobilized lysozyme with various degrees of chemical modification of anisic aldehyde and depending on this by different degree of bacteriolytic activity and sorption characteristics.
EFFECT: technical result of invention is the creation of a more efficient hemocompatible sorbent with improved properties with the help of additional preliminary chemical modification of lysozyme with anisic aldehyde before immobilization of lysozyme and method for its creation.
3 cl, 1 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD N1 FOR PREPARING A SORBENT BASED ON COVALENT IMMOBILIZED AND CHEMICALLY MODIFIED LYSOZYME FOR SORPTION OF BACTERIAL ENDOTOXINS AND THE SORBENT ITSELF | 2019 |
|
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| METHOD FOR SORPTION REMOVAL OF WHOLE PATHOGENIC BACTERIAL CELLS FROM SOLUTION USING AUTOCLAVED IMMOBILIZED LYSOZYME | 2019 |
|
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| METHOD OF LYSOCYME COVALENT IMMOBILIZATION FOR SUBSEQUENT APPLICATION OF IMMOBILIZED LYSOZYME TO REDUCE BACTERIAL POPULATION OF BIOLOGICAL FLUIDS | 2018 |
|
RU2694883C1 |
| METHOD OF REMOVING ENDOTOXINS FROM BIOLOGICAL FLUIDS USING COVALENTLY IMMOBILIZED LYSOZYME AS LIGAND | 2018 |
|
RU2684639C1 |
| SORBENT FOR REMOVAL OF IMMUNOGLOBULINS | 2008 |
|
RU2389022C2 |
| SORBENT FOR COMBINED REMOVAL FROM HUMAN PLASMA OF ATHEROGENIC LIPOPROTEIDS AND C-REACTIVE PROTEIN | 2019 |
|
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| SORBENT AND METHOD OF PREPARATION THEREOF | 2001 |
|
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| SORPTION MATERIAL, METHOD OF ITS PRODUCTION AND METHOD OF ITS APPLICATION | 2016 |
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| METHOD OF PRODUCING ALPHA-FETOPROTEIN IMMOBILIZED ON PET MICROPARTICLES | 2018 |
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RU2731415C2 |
