METHOD FOR SORPTION REMOVAL OF WHOLE PATHOGENIC BACTERIAL CELLS FROM SOLUTION USING AUTOCLAVED IMMOBILIZED LYSOZYME Russian patent published in 2020 - IPC C12N9/36 C12N11/10 

Abstract RU 2734538 C1

FIELD: biotechnologies.

SUBSTANCE: invention relates to the biotechnology. Disclosed is a method for sorption removal of whole pathogenic bacterial cells from a biological fluid, involving passing a suspension of bacterial cells through a column with a sorbent with an aminated macroporous polysaccharide matrix with autoclaved, covalently immobilized lysozyme. Autoclaving of the immobilized lysozyme in the sorbent composition is carried out at temperature of 121 °C for 30 minutes.

EFFECT: method provides sorption removal of whole pathogenic bacterial cells without their destruction.

1 cl, 2 dwg, 1 ex

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RU 2 734 538 C1

Authors

Levashov Pavel Andreevich

Adamova Irina Yurevna

Nelyub Vladimir Aleksandrovich

Ovchinnikova Ekaterina Dmitrievna

Borodulin Aleksej Sergeevich

Matolygina Darya Andreevna

Aleshina Nataliya Vasilevna

Dates

2020-10-20Published

2019-12-11Filed