FIELD: medicine.
SUBSTANCE: method for prediction of the risk of breast cancer development in a female individual that does not suffer from breast cancer, includes: determination of the level of pro-neurotensin 1-117 with amino acid sequence represented on SEQ ID No. 5, or its fragments from at least 5 amino acids or peptides containing this pro-neurotensin 1-117, obtained from the biological fluid of the specified female individual, selected from the group consisting of blood, serum, plasma, urine, cerebrospinal fluid and saliva, where pro-neurotensin 1-117 level is determined on an empty stomach; and correlation of the specified level of pro-neurotensin 1-117 or its fragments, or peptides containing pro-neurotensin 1-117, with the risk of breast cancer development, where an elevated level is prognostic for the increased risk of breast cancer.
EFFECT: method allows to effectively predict the risk of breast cancer development in a female individual.
14 cl, 2 dwg, 10 tbl, 5 ex
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Authors
Dates
2018-01-25—Published
2013-03-08—Filed