FIELD: biotechnology.
SUBSTANCE: method for prediction of cryoglobulinemic vasculitis development in patients with chronic hepatitis C (CHC) is proposed. A sample of the patient's genomic DNA is obtained, polymorphisms are detected in the ITGB3 1565 T/C and PAI-I-675 5G/4G genes, followed by analysis of their combination. The risk of cryoglobulinemic vasculitis development is determined by the formula.
EFFECT: invention allows to isolate a high-risk group for cryoglobulinemic vasculitis development among patients with CHC and to recommend intensive antiviral therapy for these patients.
4 dwg, 7 tbl, 6 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTION OF RISK OF FORMATION OF SUB-AND DECOMPENCATED PLACENTARY INSUFFICIENCY IN FAMILIES WITH THROMBOPHILIA OF BOTH PARENTS | 2017 |
|
RU2637873C1 |
METHOD OF DIAGNOSTICS OF GENETIC DISORDERS IN PATHOLOGY OF HUMAN REPRODUCTION PROCESS | 2017 |
|
RU2665827C1 |
METHOD FOR PREDICTION OF THROMBUS FLOTATION IN INFERIOR VENA CAVA WITH USING MOLECULAR GENETIC MONITORING ADDITIONALLY | 2012 |
|
RU2517215C2 |
METHOD OF PREDICTION OF ASPIRIN RESISTANCE | 2015 |
|
RU2602664C1 |
METHOD FOR PROGNOSIS OF SEVERITY OF DISSEMINATED BLOOD COAGULATION ACUTE SYNDROME USING INTRAVASCULAR GENETIC MONITORING | 2005 |
|
RU2303262C2 |
METHOD FOR EARLY PREDICTION OF CHORION AND PLACENTA DETACHMENT ON BASIS OF DETECTING GENE POLYMORPHISM OF TYPE 1 PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) | 2012 |
|
RU2494400C1 |
METHOD OF PREDICTING FAST VIROLOGICAL RESPONSE IN PATIENTS WITH CHRONIC HEPATITIS C | 2013 |
|
RU2563812C2 |
METHOD FOR GAMETE QUALITY PREDICTION IN WOMEN INFERTILITY TREATMENT FOR AUXILIARY REPRODUCTIVE TECHNOLOGIES PROGRAMS, BASED ON PATIENT'S GENOTYPE | 2016 |
|
RU2618421C1 |
METHOD FOR DIAGNOSING THROMBINEMIA IN PATIENTS WITH COVID-19 INFECTION | 2022 |
|
RU2794035C1 |
METHOD FOR ASSESSMENT OF CONTRIBUTION OF FETAL THROMBOPHILIA IN FORMATION OF SUB- AND DECOMPENSATED FORMS OF PLACENTAL INSUFFICIENCY | 2017 |
|
RU2677466C1 |
Authors
Dates
2018-01-25—Published
2016-11-03—Filed