FIELD: biotechnology.
SUBSTANCE: method for prediction of cryoglobulinemic vasculitis development in patients with chronic hepatitis C (CHC) is proposed. A sample of the patient's genomic DNA is obtained, polymorphisms are detected in the ITGB3 1565 T/C and PAI-I-675 5G/4G genes, followed by analysis of their combination. The risk of cryoglobulinemic vasculitis development is determined by the formula.
EFFECT: invention allows to isolate a high-risk group for cryoglobulinemic vasculitis development among patients with CHC and to recommend intensive antiviral therapy for these patients.
4 dwg, 7 tbl, 6 ex
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