FIELD: medicine.
SUBSTANCE: what is presented is a method for early prediction of chorion and placenta detachment. The DNA is recovered, and the gene polymorphism -675 5G>4G of type I plasminogen activator inhibitor (PAI-1) is amplified by the PCR procedure. A probability of chorion and placenta detachment in females with a high risk of self-induced reproductive losses associated with the genotype 4G/4G is predicted as 50.0%, with the genotype 4G/5G - as 35.3%.
EFFECT: invention enables a relatively high accuracy for the purpose of early prediction of a probability of chorion and placenta detachment that promotes the more rational pregnancy follow-up and better pregnancy termination.
3 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTION OF CHORION SEPARATION IN FIRST TRIMESTER OF PREGNANCY | 2014 |
|
RU2566729C1 |
| METHOD FOR PREDICTING RISK OF HABITUAL MISCARRIAGE | 2014 |
|
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| METHOD OF PREDICTING HIGH RISK OF REPRODUCTIVE LOSS IN FIRST TRIMESTER OF PREGNANCY | 2016 |
|
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| METHOD FOR PERICONCEPTIONAL PREDICTION OF RECURRENT EARLY REPRODUCTIVE LOSSES AND PRIMARY PLACENTAL INSUFFICIENCY | 2019 |
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| METHOD FOR PREDICTION OF PREMATURE ABRUPTION OF NORMALLY LOCATED PLACENTA | 2024 |
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|
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| METHOD FOR PREDICTION OF PLACENTAL INSUFFICIENCY DEVELOPMENT | 2017 |
|
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| METHOD FOR PREDICTION OF RISK OF FORMATION OF SUB-AND DECOMPENCATED PLACENTARY INSUFFICIENCY IN FAMILIES WITH THROMBOPHILIA OF BOTH PARENTS | 2017 |
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| METHOD FOR PREDICTION OF CRYOGLOBULINEMIC VASCULITIS DEVELOPMENT IN PATIENTS WITH CHRONIC HEPATITIS C | 2016 |
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| METHOD FOR PREDICTION OF NON-DEVELOPING PREGNANCY IN NORMAL EMBRYO KARYOTYPE | 2021 |
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