METHOD FOR PREDICTING AN INDIVIDUAL RISK OF INCREASED BASAL GLYCEMIA AFTER SIX MONTHS FROM THE START OF STATIN THERAPY Russian patent published in 2018 - IPC G01N33/49 

Abstract RU 2642986 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely cardiology, therapy and endocrinology, and concerns predicting an individual risk of increased basal glycemia six months after initiation of statin therapy. To do this, prior to treatment, the basal glucose level, total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol are determined. Value of the discriminant function (d) is calculated by the formula: d = OXC*(0.214) + TG*(0.809) + CH-LDL/CH-HDL*(0.346) + basal glucose * (-0.252) + a, where a is a constant of the displacement of the canonical linear discriminant function equal to -2.633. When value (d) is greater than -0.038, an individual risk of increased basal glycemia is predicted, and when value (d) is less than -0.038, the absence of basal glycemia increase in six months from the start of statin therapy is predicted.

EFFECT: method allows identifying patients with high risk of increased basal glycemia with high accuracy and, accordingly, timely prevention of carbohydrate metabolism disorders.

1 cl, 2 ex, 4 tbl

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RU 2 642 986 C1

Authors

Koshelskaya Olga Anatolevna

Sushkova Anastasiya Sergeevna

Vinnitskaya Irina Vladimirovna

Zhuravleva Olga Aleksandrovna

Brazovskaya Nataliya Georgievna

Suslova Tatyana Evgenevna

Kravchenko Elena Sergeevna

Karpov Rostislav Sergeevich

Dates

2018-01-29Published

2017-03-27Filed