FIELD: pharmacology.
SUBSTANCE: invention relates to pyridoxine-based compounds of the general formula I:
,
where at L=-S-; n=2, A=HCl; at L=-SS-; n=2, A=HCl; at L=-S(O)-; n=2, A=HCl; at L=-S(O)2-; n=2, A=HCl; at L=-S-; n=0; at L=-SS-; n=0; at L=-S(O)-; n=0; at L=-S(O)2-; n=0; at L=-S-; n=2, A=HBr; at L=-SS-; n=2, A=HBr; at L=-S(O)-; n=2, A=HBr; at L=-S(O)2-; n=2, A=HBr; at L=-S-; n=1, A=H2SO4; at L=-SS-; n=1, A=H2SO4; at L=-S(O)-; n=1, A=H2SO4; at L=-S(O)2-; n=1, A=H2SO4;
at 
;
at 
;
at 
;
at 
.
EFFECT: high level of glucokinase activation.
2 cl, 3 dwg, 23 ex
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