FIELD: medicine.
SUBSTANCE: method includes the steps of obtaining of initial angiographic frames series, subtraction frames series formation from the initial angiographic frames series, determination of frames of the subtraction frames series, corresponding to the circulation phases borders. The frame corresponding to the time of the end of the arterial phase, maximum capillary filling, start of the venous phase, end of the venous phase is determined, creating a composite image and placing visual attributes to identify the individual phases of circulation on a composite image. To each frame of the subtraction frame series, guidance and sensor filter of at least one configuration is applied, image response energy to the guidance and sensor filter is calculated in each frame of the subtraction frame series, the frame that corresponds to the time of arterial phase end is determined by the first maximum energy response among the subtraction frame series, the frame that corresponds to the time of maximum capillary filling, based on the minimum response energy obtained after the arterial phase end, a frame corresponding to the beginning of the venous phase is determined by the first maximum response energy obtained after maximum capillary filling, a frame corresponding to the end of the venous phase, is determined by the minimum response energy obtained after the beginning of the venous phase. The method also contains steps including reception of the initial angiographic frames series, formation of subtraction frames series from the initial angiographic frames series, determination on the minimum brightness of pixels on the frame for each frame of the subtraction series, based on which, frames of the subtraction frames series that correspond to the circulation phases borders are determined, namely a frame of the maximum capillary filling, beginning of the arterial phase, at that, a composite image is generated for at least one circulation phase and visual attributes are placed to identify the individual phases of circulation on a composite image. For each frame of the subtraction frames series, vessels the number of pixels in the vessels image is additionally determined. For each frame of the subtraction frames series, the product of the number of pixels in the blood vessels image and the minimum brightness of the pixels in the frame is determined, a frame corresponding to the time of maximum capillary filling, is determined by the maximum value of the product received among frames of the subtraction frames series, for every two adjacent frames of the subtraction frames series, the value of the difference between the corresponding values of the product received is determined as a frame, corresponding to the beginning of the arterial phase, a frame is selected, for which the value of the received difference exceeds the specified threshold. The method also contains steps, including obtaining of the initial angiographic frames series, determination of frames of the initial angiographic frames series corresponding to the circulation phases borders, namely the definition of a frame of the arterial phase beginning and maximum capillary filling, at that, a composite image is generated for at least one circulation phase and visual attributes are placed to identify the individual phases of circulation on a composite image, for each frame of the initial angiographic frames series, an image is selected corresponding to the areas of interest for elements of which the specified brightness characteristic is determined. The first frame, for which the specified brightness for the selected image changed by the specified value when compared with the value of the same brightness for the selected image on the previous frame, is selected as a frame corresponding to the beginning of the arterial phase, a frame for which the specified brightness for the selected image is the most different from the value of the same brightness for the selected image on the first frame of the initial angiographic series, is selected as the frame corresponding to the time of maximum capillary filling.
EFFECT: increased accuracy of circulation phases borders determination.
5 cl, 8 dwg
Authors
Dates
2018-02-14—Published
2016-08-03—Filed