FIELD: pharmacology.
SUBSTANCE: multivalent antigenic composition contains an adjuvant and two or more polypeptide, where two or more polypeptide include: I) polypeptide containing a sequence of α-lactalbumin SEQ ID NO: 1, and polypeptide containing sequence αS1-casein SEQ ID NO: 2; II) polypeptide containing a sequence of α-lactalbumin SEQ ID NO: 1, and polypeptide containing the sequence β-casein SEQ ID NO: 3; or III) polypeptide containing the sequence α-lactalbumin SEQ ID NO: 1, and polypeptide containing the sequence κ-casein SEQ ID NO: 4. The group of inventions also relates to a method of induction of an antigen-specific immune response, as well as a method of activating human T-cells in vitro. Activation of T-cells, which are CD4 + and CD8 + cells.
EFFECT: induction of inflammatory response, specific breast tissue, in a patient.
21 cl, 27 dwg, 10 ex
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Authors
Dates
2018-02-15—Published
2013-04-15—Filed