MULTIVALENT VACCINE AGAINST BREAST CANCER Russian patent published in 2018 - IPC A61K35/20 A61K38/38 A61K35/17 A61P35/00 

Abstract RU 2645085 C2

FIELD: pharmacology.

SUBSTANCE: multivalent antigenic composition contains an adjuvant and two or more polypeptide, where two or more polypeptide include: I) polypeptide containing a sequence of α-lactalbumin SEQ ID NO: 1, and polypeptide containing sequence αS1-casein SEQ ID NO: 2; II) polypeptide containing a sequence of α-lactalbumin SEQ ID NO: 1, and polypeptide containing the sequence β-casein SEQ ID NO: 3; or III) polypeptide containing the sequence α-lactalbumin SEQ ID NO: 1, and polypeptide containing the sequence κ-casein SEQ ID NO: 4. The group of inventions also relates to a method of induction of an antigen-specific immune response, as well as a method of activating human T-cells in vitro. Activation of T-cells, which are CD4 + and CD8 + cells.

EFFECT: induction of inflammatory response, specific breast tissue, in a patient.

21 cl, 27 dwg, 10 ex

Similar patents RU2645085C2

Title Year Author Number
DNA COMPOSITION FOR INDUCING IMMUNE RESPONSE ON TUMOUR-ASSOCIATED MACROPHAGUES 2007
  • Rejsfeld Ral'F A.
  • Sjan Zhun
  • Lo Jun'Pin
RU2459631C2
PEPTIDE VACCINES FOR CANCER EXPRESSING MPHOSPH1 OR DEPDC1 POLYPEPTIDES 2007
  • Fudzioka Tomoaki
  • Nakamura Jusuke
  • Tsunoda Takuja
  • Osava Rjudzi
  • Sida Midori
RU2469044C2
HOMODIMER PROTEIN CONSTRUCTION 2011
  • Ruffini Per Adelki
  • Bogen Byarne
  • Fredriksen Agnete Brunsvik
RU2624041C2
PROSTATE-ASSOCIATED ANTIGENS AND IMMUNOTHERAPY SCHEMES BASED ON VACCINES 2013
  • Binder Dzhozef Dzhon
  • Chou Khelen Kim
  • Dermier Majkl Robert
  • Joss Karin Yute
  • Pies Brajen Gregori
  • Ten Dzhojs Tsi
  • Tsaj Van To
RU2609651C2
ANTIBODY AGAINST CLAUDIN 18A2 AND APPLICATION THEREOF 2017
  • Van, Pen
  • Tszyan, Khua
  • Yan, Linlin
  • Shi, Chzhimin
  • Van, Khuamao
  • Li, Tszunkhaj
RU2793445C2
VERSIONS OF IL-21 2006
  • Khert Siu Annegrete
  • Bondensgaard Kent
  • Madsen Dennis
RU2412199C2
AMPLIFIER T-CELL RESPONSE TO VACCINE 2018
  • Nikosia, Alfredo
  • Skarselli, Elisa
  • Folgori, Antonella
  • Lam, Amin
RU2794196C2
PROSTATE-ASSOCIATED ANTIGENS AND IMMUNOTHERAPEUTIC REGIMENS BASED ON VACCINES 2013
  • Binder, Joseph John
  • Cho, Helen Kim
  • Dermyer, Michael Robert
  • Jooss, Karin Ute
RU2737765C2
IMMUNOPROPHYLACTIC CANCER VACCINE 2004
  • Agadzhanjan, Majkl, G.
  • Gochikjan, Anait
RU2556128C2
POLYPEPTIDES 2011
  • Gaudernakk Gustav
  • Rasmussen Anne-Marija
  • Suso Else Marit Inderberg
RU2581800C2

RU 2 645 085 C2

Authors

Tuokhi Vinsent K.

Dates

2018-02-15Published

2013-04-15Filed