FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to obtaining multi- antigen DNA constructs, expression vectors, containing said constructs, and pharmaceutical compositions, that can be used in medicine. Multi- antigen DNA constructs are obtained for expression of the immunogenic polypeptides of prostate-specific antigens PSA, PSCA, PSMA, that is used in a composition for inhibiting the abnormal cell proliferation or inducing an immune response against prostate-associated antigen in mammals.
EFFECT: invention allows with high efficiency to treat prostate cancer in humans.
24 cl, 43 dwg, 33 tbl, 20 ex
| Title |
Year |
Author |
Number |
| PROSTATE-ASSOCIATED ANTIGENS AND IMMUNOTHERAPEUTIC REGIMENS BASED ON VACCINES |
2013 |
- Binder, Joseph John
- Cho, Helen Kim
- Dermyer, Michael Robert
- Jooss, Karin Ute
|
RU2737765C2 |
| VECTORS FOR EXPRESSION OF PROSTATE-ASSOCIATED ANTIGENS |
2014 |
- Binder Joseph John
- Cho Helen Kim
|
RU2650860C2 |
| ANTIBODIES TO PD-1 AND METHODS OF THEIR APPLICATION |
2015 |
- Abdiche Yasmina Noubia
- Cho Helen Kim
- Ho Weihsien
- Jooss Karin Ute
- Rajpal Arvind
- Youssef Sawsan
|
RU2701797C2 |
| USING MVA (MODIFIED VACCINIA ANKARA) FOR TREATING PROSTATE CANCER |
2008 |
- Del'Kehr Alen
- Laus Rajner
- Mehndl Stefani
- Rauntri Rajan Blehr
- Legrand Fatema
|
RU2499606C2 |
| ANTI-CANCER VACCINES TARGETING PRAME AND THEIR APPLICATIONS |
2018 |
- Yan, Jian
- Slager, Anna
- Garman, Bradley
- Cooch, Neil
|
RU2748903C1 |
| ANTICANCER VACCINES TARGETING BORIS AND METHODS OF THEIR APPLICATION |
2018 |
- Yan, Jian
- Slager, Anna
- Garman, Bradley
- Cooch, Neil
|
RU2759681C1 |
| BORIS-TARGETED ANTI-CANCER VACCINES AND METHODS FOR APPLICATION THEREOF |
2018 |
- Yan, Tszyan
- Slager, Anna
- Garman, Bredli
- Kuch, Nil
|
RU2799786C2 |
| MESOTHELINE-TARGETED CANCER VACCINES AND THEIR APPLICATION |
2018 |
- Yan, Jian
- Slager, Anna
- Garman, Bradley
- Cooch, Neil
|
RU2751252C1 |
| FUSED PROTEINS WITH IMMUNOGLOBULIN FC-FRAGMENT FOR ENHANCING IMMUNOGENICITY OF PROTEIN AND PEPTIDE ANTIGENS |
2000 |
- Dzhilliz Stefen D.
- Lo Kin Ming
- Vesolovski Dzhon S. Dzhr.
|
RU2248214C2 |
| NUCLEIC ACID SYNTHETIC MOLECULE (VERSIONS), MAMMAL CELL EXPRESSION VECTOR, MAMMAL HOST CELL AND METHOD OF EXPRESSING ANTIGEN PROTEIN OF HUMAN EPIDERMAL GROWTH FACTOR-2 (HER2/neu) OR SHORTENED FORM THEREOF |
2004 |
- Gallo Paskual'
- Monachi Paolo
- Nutstso Mauritsio
|
RU2397249C2 |
