FIELD: medicine.
SUBSTANCE: invention relates to medicine, specifically to gynecology and reproductive medicine. Method employs daily administration of a granulocyte colony-stimulating factor (G-CSF) under the skin of the forearm in a dose of 0.2 ml of the officinal drug solution in a dose of 30,000,000 units per 1.0 ml of the solution, from the second day of the menstrual cycle to the pregnancy test at 28±3 day of the menstrual cycle. Method comprises 4–5 intrauterine installations of G-CSF with an interval of 1–2 days in the follicular phase of the menstrual cycle after the end of menstruation in a volume of 1.0 ml of the official solution for each installation, performed with a catheter for embryo transfer. In "ART protocols", the last intra-uterine administration of G-CSF is performed 1 day before embryo transfer.
EFFECT: method improves efficiency of embryo implantation in the natural cycle of conception and in assisted reproductive technology (ART) protocols.
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