METHOD FOR MONITORING VIOLATIONS OF MICROHEMODYNAMICS IN THE PANCREAS OF LABORATORY RATS Russian patent published in 2018 - IPC A61B5/02 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely the monitoring of microhemodynamics in the pancreas during surgery using speckle-contrast imaging technology. Method comprises the following stages: recording R series from Q speckle images of the pancreas investigated region, wherein each series of speckle images r are recorded within maximum one second. For each speckle image q the average intensity of the scattered light and the root-mean-square value of the fluctuations σ_Iq of scattered light intensity are determined. Averaging of and σ_I by Q speckle images in one series is performed. For each series of speckle pictures r, the contrast value is calculated. Contrast value K_r for different series of speckle images is compared and in the presence of a difference between the values a conclusion is made about qualitative violation of microhemodynamics. Calibration series is also preliminarily recorded from the Q speckle images of a phantom that simulates blood flow at a given velocity υ. For each speckle image q the average intensity of the scattered light and the root-mean-square value of the fluctuations σ_Iq of scattered light intensity are determined. Averaging of and σ_I by Q speckle images in the calibration series is performed. For the calibration series of speckle images, the contrast value is calculated. Correlation time τ_c is calculated from the dependence of K (τ_c). Coefficient a is calculated from the dependence u (τ_c, a). Absolute value of the blood flow velocity υ_q (a, K_r) is calculated for each series from the Q speckle images of the study area.

EFFECT: comparing υ_q for different series of speckle images, the conclusion is made about quantitative violation of microhemodynamics; invention makes it possible to expand the functionality and improve the accuracy of monitoring the violations of microhemodynamics.

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