FIELD: medicine.
SUBSTANCE: group of inventions refers to medical technology, namely to the means for radiotherapy and medical imaging. Radiotherapy system contains the block of three-dimensional visualization in real time, which generates the base image and three-dimensional real-time image of at least a portion of the body region of the subject including the target and one or more bodies at risk (ODA), the recording unit that deformably registers the plan image of the body region of the subject and the base image, and also maps the capability of the tissue to absorb radiation in the planned image onto the base image, the motion block that measures the movement of the target volume and ODA in the process of radiotherapy based on the real-time images, and the real-time dose calculation subsystem that calculates the irradiation dose based on the ability of the tissue to absorb radiation applied as the map from the base image or the plan image to three-dimensional images in real time, the dose of irradiation in real time is based on the initial intensities of the radiation beams leading to and crossing each voxel, weakening along the trajectory of each of the radiation beams and the time, at which each beam intersects each voxel. Method of radiation therapy is provided by means of the operation of the radiation therapy system using the non-timed machine-readable storage medium for radiotherapy and the electronic data processing device for radiotherapy. Radiation therapy system according to the second option comprises the linear accelerator (LINAC), which is configured in order to generate the plurality of radiation beams into at least one target volume in the body of the subject, where each beam has the size, shape, direction, intensity and duration, which are given on the basis of the radiotherapy plan, the robot-controlled ultrasound transducer, which is designed in order to generate the 3-dimensional (3D) ultrasound images of the body region of the subject including at least one target volume and surrounding tissues, which are exposed to the plurality of radiation beams, at least one processor is configured in order to re-reconstruct the ultrasound images into three-dimensional images of the subject body during the delivery of radiation beams, deformably register the X-ray computer tomography (CT) image and basic image of ultrasound images that are generated before the therapy, and to apply the map of tissue densities based on the CT scan to basic three-dimensional US images to create three-dimensional maps of tissue densities, measure the movements of the target volume and surrounding tissues from the three-dimensional images, which are generated during the delivery of radiation beams, register the three-dimensional map of tissue densities on the three-dimensional ultrasound images, which are generated during the delivery of radiation beams, and calculate the radiation dose in real time, and ultrasound images in real time are generated during the delivery of radiation beams, the real-time dose of irradiation is based on the initial intensities of the radiation beams leading to and crossing each voxel, weakening along the trajectory of each of the radiation beams and of the time, at which each beam intersects each voxel, and the measured motion, and at least one of the LINAC controls based on the calculated dose in real time and controlling the display to display the planned image in combination with the calculated dose in real time.
EFFECT: use of inventions makes it possible to improve the adaptive calculation of doses in real time for radiation therapy.
20 cl, 2 dwg
