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2 648 445

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IPC

A61K31/472(2006-01-01)

A61K47/12(2006-01-01)

A61K47/32(2006-01-01)

A61K47/38(2006-01-01)

A61P29/00(2006-01-01)

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Application

2016143500, 2016-11-03

(24)

Start date

2016-11-03

(22)

Actual filing date

2016-11-03

(45)

Published

2018-03-26

(72)

Inventor

Astafeva Svetlana AsylkhanovnaBurlutskaya Anna AlbertovnaVdovina Galina PetrovnaGorbunov Aleksej ArkadevichZenkova Elena AndreevnaKoryukina Irina PetrovnaSmolyak Andrej AlekseevichStrelnikov Vladimir NikolaevichChugunova Mariya PetrovnaShklyaev Yurij Vladimirovich

(73)

Holder

Astafeva Svetlana AsylkhanovnaVdovina Galina PetrovnaGorbunov Aleksej ArkadevichKoryukina Irina PetrovnaSmolyak Andrej AlekseevichStrelnikov Vladimir NikolaevichShklyaev Yurij Vladimirovich

6-(3,3-DIMETHYL-3,4-DIHYDROISOCHINOLIN-1-IL) AMINOHEXANE ACID AND PHARMACEUTICAL COMPOSITION ON ITS BASIS THAT HAVE ANALGETIC ACTIVITY Russian patent published in 2018 - IPC A61K31/472 A61K47/12 A61K47/32 A61K47/38 A61P29/00

Abstract RU 2648445 C1

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine, pharmaceutical chemistry, pharmacology and pharmaceutics. Use of 6-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl) aminohexane acid of the formula I as a compound, providing analgesic effect and helps to relieve the mechanical somatic pain during diseases, accompanied by frank pain syndrome, and pharmaceutical composition based on it. 1.

EFFECT: technical result of the invention is to implement a stated purpose with efficiency comparable to ketorolac with low toxicity; pharmaceutical composition provides a prolonged analgesic effect 8 hours after oral intake to rats.

2 cl, 14 tbl

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RU 2 648 445 C1

Authors

Astafeva Svetlana Asylkhanovna

Burlutskaya Anna Albertovna

Vdovina Galina Petrovna

Gorbunov Aleksej Arkadevich

Zenkova Elena Andreevna

Koryukina Irina Petrovna

Smolyak Andrej Alekseevich

Strelnikov Vladimir Nikolaevich

Chugunova Mariya Petrovna

Shklyaev Yurij Vladimirovich

Dates

2018-03-26—Published

2016-11-03—Filed