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2 808 905

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IPC

C07D487/22(2006-01-01)

A61K31/55(2006-01-01)

A61P25/04(2006-01-01)

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Application

2023109790, 2023-04-17

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Start date

2023-04-17

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Actual filing date

2023-04-17

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Published

2023-12-05

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Inventor

Krylova Svetlana GennadevnaPoveteva Tatyana NikolaevnaSuslov Nikolaj InnokentevichZueva Elena PetrovnaNesterova Yuliya VladimirovnaAfanaseva Olga GennadevnaKulpin Pavel ValerevichKiseleva Elena AleksandrovnaRybalkina Olga YurevnaZhdanov Vadim VadimovichBajbakova Olga VladimirovnaEremina Valeriya ValerevnaKulagina Darya AleksandrovnaAlekseeva Natalya AlekseevnaChikina Majya ViktorovnaSysolyatin Sergej Viktorovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Problem Khimiko-Energeticheskikh Tekhnologij Sibirskogo Otdeleniya Rossijskoj Akademii Nauk So Ran)Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Natsionalnyj Issledovatelskij Meditsinskij Tsentr Rossijskoj Akademii Nauk" Nimts)

4-(2-ETOXYACETYL)-2,6,8,10,12-PENTAACETYL-2,4,6,8,10,12-HEXAAZATETRACYCLO [5,5,0,0,0] DODECANE AS ANALGETIC AND METHOD OF ITS OBTAINING Russian patent published in 2023 - IPC C07D487/22 A61K31/55 A61P25/04

Abstract RU 2808905 C1

FIELD: pharmaceutical chemistry; pharmacology.

SUBSTANCE: invention relates to a new chemical compound 4-(2-ethoxyacetyl)-2,6,8,10,12-pentaacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,0,0^3,11,0^5,9]dodecane of formula (I). The invention also relates to a method of its preparation, which consists in the acylation of 2,6,8,10,12-pentaacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,0,0^3,11,0^5,9]dodecane with 2-ethoxyacetic acid chloride.

EFFECT: identification of the analgesic activity of 4-(2-ethoxyacetyl)-2,6,8,10,12-pentaacetyl-2,4,6,8,10,12-hexaazatetracyclo[5,5,0,0^3,11,0^5,9]dodecane, as well as the implementation of the method of its preparation.

2 cl, 7 tbl, 2 ex

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RU 2 808 905 C1

Authors

Krylova Svetlana Gennadevna

Poveteva Tatyana Nikolaevna

Suslov Nikolaj Innokentevich

Zueva Elena Petrovna

Nesterova Yuliya Vladimirovna

Afanaseva Olga Gennadevna

Kulpin Pavel Valerevich

Kiseleva Elena Aleksandrovna

Rybalkina Olga Yurevna

Zhdanov Vadim Vadimovich

Bajbakova Olga Vladimirovna

Eremina Valeriya Valerevna

Kulagina Darya Aleksandrovna

Alekseeva Natalya Alekseevna

Chikina Majya Viktorovna

Sysolyatin Sergej Viktorovich

Dates

2023-12-05—Published

2023-04-17—Filed