GASTRAL-RESISTANT PHARMACEUTICAL OR NUTRACEUTICAL COMPOSITION WITH SUSTAINABILITY TO THE ETHANOL IMPACT Russian patent published in 2018 - IPC A61K9/32 A61K47/32 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to the field of medicine and presents the gastro-resistant pharmaceutical or nutraceutical composition, which contains the core that contains the pharmaceutical or the nutraceutical active ingredient, and the gastro-resistant coating layer, where the mentioned coating layer contains at least 30 wt% of (meth)acrylate copolymer, which consists of the following polymerized units: from 10 up to 40 wt% of methacrylic acid, from 10 up to 50 wt% of ethyl acrylate, from 10 up to 80 wt% C₄-C₁₈ of alkyl ester of acrylic or methacrylic acid and optionally from 0 up to 20 wt% of methyl methacrylate, where the (meth)acrylate copolymer has the average molecular weight M_w, which is equal to 90,000 or more, where the release of the pharmaceutical or nutraceutical ingredient is not more than 10% under the in-vitro conditions at pH 1.2 after 2 hours in the 0.1 mole HCl medium with or without addition of 20% volume per volume of ethanol.

EFFECT: invention provides the possibility of creating the gastro-resistant composition with the reduced sensitivity to the impact of ethanol on release of the active ingredient.

13 cl, 14 ex, 3 tbl