FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to a pyrrole substituted indolone derivative of formula (I), a pharmaceutical composition, comprising said derivative, and the use of pyrrole substituted indolone derivatives for the treatment of tyrosine kinase receptor mediated diseases, such as tumors.
.
EFFECT: for the treatment of tyrosine kinase receptor mediated diseases, such as tumors.
10 cl, 20 ex, 4 tbl
Title | Year | Author | Number |
---|---|---|---|
NAPHTHALENE CARBOXAMIDE DERIVATIVES AS PROTEIN KINASE AND HISTONE DEACETYLASE INHIBITORS, METHODS FOR PREPARING AND USING THEM | 2010 |
|
RU2497809C2 |
DIHYDROINDOLONE DERIVATIVES | 2009 |
|
RU2468022C2 |
SUBSTITUTED INDOL-5-OL DERIVATIVES AND THERAPEUTIC APPLICATIONS THEREOF | 2013 |
|
RU2674249C2 |
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF ACUTE MYELOID LEUKEMIA OR METASTATIC MAMMARY GLAND CANCER | 2018 |
|
RU2763346C2 |
QUINAZOLINONE DERIVATIVE, A METHOD FOR PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND USE THEREOF | 2017 |
|
RU2730500C2 |
PROTEIN TYROSINE KINASE ACTIVITY INHIBITORS | 2009 |
|
RU2533827C2 |
(S)-4-OXO-N-(1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDROBENZO[a]HEPTALEN-7-yl)PENTANAMIDE DERIVATIVE AND ITS USE | 2022 |
|
RU2809516C1 |
PROTEINKINASE INHIBITORS, METHOD FOR OBTAINING THEREOF AND MEDICAL APPLICATION | 2016 |
|
RU2749437C2 |
IMIDAZO[1,2-b]PYRIDAZINE AND PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AND USE THEREOF AS PROTEIN KINASE INHIBITOR | 2007 |
|
RU2487875C2 |
NOVEL PYRIMIDINE AMIDE DERIVATIVES AND USE THEREOF | 2003 |
|
RU2378267C2 |
Authors
Dates
2018-04-17—Published
2015-02-04—Filed