FIELD: medicine.
SUBSTANCE: invention relates to a compound represented by the chemical formula 1 or its pharmaceutically acceptable salt, where R1 is hydrogen, R2 is fluor or C1-C4 alkyl composite ester, and R3 is structures (a), (b), (c) or (d). the invention also relates to a pharmaceutical composition for the prevention or treatment of a disease associated with the inhibition of FLT3 kinase containing (a) effective amount of the compound represented by the chemical formula 1 or its pharmaceutically acceptable salt; and (b) a pharmaceutically acceptable carrier.
EFFECT: obtaining compounds having inhibiting capability relatively to FLT3.
formula 1,
(а), (b), (c), (d)
5 cl, 4 tbl, 6 dwg, 5 ex
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Authors
Dates
2021-12-28—Published
2018-10-30—Filed