FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, namely to production of expression vector comprising (a) C68 nucleotide sequence and (b) multi-antigenic DNA construct, which codes for immunogenic polypeptides of prostate-associated antigens (RAA), which can be used in medicine. Expression vector C68 is obtained recombinantly, which is used as part of a pharmaceutical composition to elicit an immune response to RAA.
EFFECT: invention allows to increase the effectiveness of treatment of prostate cancer in humans.
24 cl, 13 dwg, 15 tbl, 11 ex
Title | Year | Author | Number |
---|---|---|---|
CHIMERIC ANTIGEN RECEPTORS AIMED AT PSCA | 2016 |
|
RU2759879C2 |
IMMUNE CELLS EXPRESSING INVERSE UNIVERSAL CHIMERIC ANTIGEN RECEPTOR, FOR TARGETING VARIOUS MULTIPLE ANTIGENS AND METHOD FOR PRODUCTION AND USE THEREOF FOR TREATING CANCER, INFECTIONS AND AUTOIMMUNE DISEASES | 2019 |
|
RU2824391C2 |
CHIMERIC CYTOKINE RECEPTOR | 2016 |
|
RU2826122C1 |
AMATOXIN ANTIBODY-DRUG CONJUGATES AND USE THEREOF | 2020 |
|
RU2826004C2 |
BISPECIFIC FUSION PROTEIN AND ITS USE | 2021 |
|
RU2801528C2 |
HUMANIZED ANTI-PSMA ANTIBODIES | 2019 |
|
RU2794450C2 |
IL-12 HETERODIMERIC FC FUSION PROTEINS | 2019 |
|
RU2819097C2 |
IMPROVED ANTIGEN-BINDING RECEPTORS | 2018 |
|
RU2825816C2 |
MODIFIED HEMATOPOIETIC STEM CELLS/PROGENITOR CELLS AND NON-T EFFECTOR CELLS, AND USE THEREOF | 2014 |
|
RU2733652C2 |
INSECTICIDE PROTEINS OF PLANT ORIGIN AND THEIR APPLICATION METHODS | 2016 |
|
RU2762832C2 |
Authors
Dates
2018-04-17—Published
2014-10-17—Filed