STABLE MULTIPLE ANTIGEN-BINDING ANTIBODIES Russian patent published in 2018 - IPC C07K16/00 C07K16/22 A61K39/395 A61P35/00

Abstract RU 2652886 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to biochemistry, in particular to a method for modifying two light chain domains to produce an antibody with enhanced stability, as compared to an antibody not containing said substitutions.

EFFECT: invention allows to obtain antibodies with enhanced stability, as compared to antibodies not containing said substitutions.

22 cl, 4 ex, 14 tbl

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RU 2 652 886 C2

Authors

Rigler Astrid K.

Borras Leonardo

Sommavilla Roberto

Dates

2018-05-03—Published

2012-10-19—Filed