FIELD: biotechnology.
SUBSTANCE: set of oligonucleotide samples for determination of the human mitochondrial DNA genotype, characterized by the fact that this set allows to determine the human mitochondrial DNA genotype in 38 single nucleotide sites located in different parts of the mitochondrial genome and polymorphic in Russian populations of different ethnic origin, using the enzymatic single nucleotide extension method for a hybridized sample. The structure of oligonucleotide samples takes into account the variability of DNA in nearby sites and grouping of genotyped sites in 3 panels for multiplex reactions.
EFFECT: improved method.
3 dwg, 2 tbl
Title | Year | Author | Number |
---|---|---|---|
Method for obtaining molecular single nucleotide markers for determining the probable ethnogeographic origin of a person, a set of oligonucleotides for implementing the method | 2021 |
|
RU2800082C2 |
SYNTHETIC OLIGONUCLEOTIDE PRIMERS AND METHOD FOR GENETIC TYPING FOR PERSONAL IDENTIFICATION BY Y-CHROMOSOME MICROSATELLITE DNA MARKERS SYSTEM | 2012 |
|
RU2528742C2 |
METHOD, TEST-SYSTEM AND PRIMERS FOR DETERMINATION OF HAPLOGROUPS OF HUMAN Y-CHROMOSOME | 2013 |
|
RU2558231C2 |
METHOD OF PRODUCING FULL-LENGTH HUMAN MITOCHONDRIAL DNA SEQUENCE USING SET OF OLIGONUCLEOTIDES BY MULTIPLEX AMPLIFICATION FOR WORKING WITH DEGRADED DNA SAMPLES | 2021 |
|
RU2818323C2 |
SYSTEM AND METHOD OF INTERPRETING DATA AND PROVIDING RECOMMENDATIONS TO USER BASED ON GENETIC DATA THEREOF AND DATA ON COMPOSITION OF INTESTINAL MICROBIOTA | 2017 |
|
RU2699284C2 |
SET OF DIFFERENTIATING NUCLEOTIDES AND BIOCHIP APPLICABLE IN METHOD FOR GENETIC TYPING OF HUMAN Y-CHROMOSOMES HAPLOGROUP MARKERS: M130 (C), M145 (DE) | 2012 |
|
RU2539733C2 |
SET OF STR-MARKERS OF THE Y-CHROMOSOME FOR DETERMINING THE ETHNO-TERRITORIAL ORIGIN OF AN INDIVIDUAL BASED ON A SAMPLE OF HIS DNA | 2021 |
|
RU2804433C2 |
Method for obtaining molecular single nucleotide markers for identifying an unknown individual by multiplex amplification for working with samples of degraded DNA, a kit for obtaining molecular markers | 2021 |
|
RU2800083C2 |
METHOD FOR ASSESSING GENETIC RISK OF ATHEROSCLEROSIS BASED ON DETERMINATION OF MITOCHONDRIAL GENOME VERSIONS | 2015 |
|
RU2592233C1 |
METHOD FOR MEASURING NUMBER OF COPIES OF HUMAN MITOCHONDRIAL DNA BY DIGITAL POLYMERASE CHAIN REACTION | 2021 |
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RU2755663C1 |
Authors
Dates
2018-05-03—Published
2016-06-08—Filed