FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, specifically to the novel biologically active substance 2-[2-(3-chloro-adamantan-1-yl)-2-oxoethylidenehydrazino]-4-(2,4-dimethoxyphenyl)-4-oxo-2-butenoic acid of formula 1. 
.
EFFECT: proposed compound has a pronounced anti-flaviviral activity, low toxicity and can be used in the treatment of tick-borne encephalitis.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 4-(4-METHOXYPHENYL)-2-{2-[2-OXO-(3-CHLORO-ADAMANTAN-1-YL)-ETHYLIDENE]HYDRAZINYL}-4-OXOBUT-2-ENOATE SODIUM WITH HEMOSTATIC ACTIVITY | 2016 |
|
RU2663624C1 |
| QUINOLINO [2,1-b] QUINAZOLIN-12-ONE-5- CARBOXYLIC ACID CYCLOHEXYLAMIDE HAVING ANTIFLAVIRAL ACTIVITY | 1997 |
|
RU2130023C1 |
| N-(2-BENZOTHIAZOLYL)AMIDE OF 3-BROMO-2,4-DIOXO-4-(4-METHOXY PHENYL)BUTANOIC ACID, HAVING HYPOGLYCEMIC ACTIVITY | 2010 |
|
RU2455293C2 |
| 3-BROMO-4-(4-METHOXYPHENYL)-N-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-2,4-DIOXOBUTANAMIDE, HAVING ANTIMICROBIAL ACTION | 2018 |
|
RU2717243C2 |
| 2-HYDROXY-N-(6-METHOXYBENZO[D]THIAZOL-2-YL)-4-OXO-4-PHENYLBUT-2-ENAMIDE, HAVING GASTROPROTECTIVE AND IMMUNOMODULATORY ACTION | 2018 |
|
RU2723897C2 |
| TRIS {[1-(6-METHYLBENZO[D]THIAZOL-2-YL)AMINO-1,4-DIOXO-4-(P-TOLYL) BUT-2-EN-2-YL]OXY} IRON HAVING ANTI-INFLAMMATORY ACTION | 2018 |
|
RU2717242C2 |
| THIAZOLINE AMMONIUM 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL)-2-BUTENOATE, HAVING ANTICOAGULATION ACTIVITY | 2009 |
|
RU2461550C2 |
| N-(2-BENZOTHIAZOLYL)AMIDE 2-HYDROXY-4-OXO-4-(4-CHLOROPHENYL)-2-BUTENOIC ACID HAVING ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTIVITY | 2008 |
|
RU2396262C2 |
| 4-(4-METHYLPHENYL)-4-OXO-2-[3-(ETHOXYCARBONYL-4,5-R,R-THIOPHEN-2-YLAMINO]BUT-2-ENOIC ACID, HAVING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | 2008 |
|
RU2389724C1 |
| N-(2-THIAZOLYL)AMIDE OF 2-(2-OXO-3-INDOLINYLIDENE)HYDRAZINO-4-OXO-4-PHENYL-2-BUTENOIC ACID HAVING ANTIBACTERIAL AND ANALGESIC ACTIVITY | 2008 |
|
RU2401837C2 |
