4-(4-METHOXYPHENYL)-2-{2-[2-OXO-(3-CHLORO-ADAMANTAN-1-YL)-ETHYLIDENE]HYDRAZINYL}-4-OXOBUT-2-ENOATE SODIUM WITH HEMOSTATIC ACTIVITY Russian patent published in 2018 - IPC C07C251/74 A61K31/185 A61P7/00 

Abstract RU 2663624 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, namely to new biologically active substance 4-(4-methoxyphenyl)-2-{2-[2-oxo-(3-chloro-adamantane-1-yl)-ethylidene]hydrazinyl}-4-oxobut-2-enoate sodium of formula 1.

EFFECT: this compound has a high hemostatic activity with low toxicity.

1 cl, 1 tbl, 1 ex

Similar patents RU2663624C1

Title Year Author Number
2-(4-METHOXYPHENYLAMINO)-4-(2,4-DIMETHYLPHENYL)-1-(PIPERAZIN-1-YL)BUT-2-ENE-1,4-DIONE HYDROCHLORIDE WITH HEMOSTATIC ACTIVITY 2016
  • Pulina Natalya Alekseevna
  • Kozhukhar Vyacheslav Yurevich
  • Starkova Alla Valentinovna
  • Syropyatov Boris Yakovlevich
RU2679450C2
2-[2-(3-CHLORO-ADAMANTAN-1-YL)-2-OXOETHYLIDENEHYDRAZINO]-4-(2,4-DIMETHOXYPHENYL)-4-OXO-2-BUTENOIC ACID HAVING ANTI-FLAVIVIRAL ACTIVITY 2015
  • Pulina Natalya Alekseevna
  • Yushkova Tatyana Aleksandrovna
  • Kuznetsov Aleksandr Sergeevich
  • Rubtsov Aleksandr Evgenevich
  • Krasnova Anastasiya Ivanovna
RU2655609C2
2-{[2-(ADAMANTAN-1-YL)-2-OXOETHYLIDENEHYDRAZINYL-4-(Β-NAPHTHALYL)-4-OXOBUT-2-ENOYL]THIO} SODIUM ETHANOATE WITH WOUND HEALING AND ANTI-INFLAMMATORY ACTIVITY 2023
  • Pulina Natalia Alekseevna
  • Kuznetsov Aleksandr Sergeevich
  • Chashchina Svetlana Viktorovna
RU2808431C1
2-HYDROXY-N-(6-METHOXYBENZO[D]THIAZOL-2-YL)-4-OXO-4-PHENYLBUT-2-ENAMIDE, HAVING GASTROPROTECTIVE AND IMMUNOMODULATORY ACTION 2018
  • Pulina Natalya Alekseevna
  • Lipatnikov Konstantin Viktorovich
  • Sobin Fedor Vladimirovich
  • Yushkova Tatyana Aleksandrovna
RU2723897C2
TRIS {[1-(6-METHYLBENZO[D]THIAZOL-2-YL)AMINO-1,4-DIOXO-4-(P-TOLYL) BUT-2-EN-2-YL]OXY} IRON HAVING ANTI-INFLAMMATORY ACTION 2018
  • Pulina Natalya Alekseevna
  • Lipatnikov Konstantin Viktorovich
  • Rudakova Irina Pavlovna
  • Sobin Fedor Vladimirovich
RU2717242C2
3-BROMO-4-(4-METHOXYPHENYL)-N-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-2,4-DIOXOBUTANAMIDE, HAVING ANTIMICROBIAL ACTION 2018
  • Pulina Natalya Alekseevna
  • Lipatnikov Konstantin Viktorovich
  • Dubrovina Svetlana Sergeevna
  • Rudakova Irina Pavlovna
  • Sobin Fedor Vladimirovich
RU2717243C2
USE OF SUBSTITUTED ESTERS OF (Z)-2-(2-(DIPHENYLMETHYLENE)HYDRAZINYL)-5,5-DIMETHYL-4-OXOHEX-2-ENOIC ACID AS AN ANTIBACTERIAL AND ANTIFUNGAL AGENT 2021
  • Syutkina Alena Ivanovna
  • Makhmudov Ramiz Ragibovich
  • Shipilovskikh Sergej Aleksandrovich
RU2768761C1
2-(1,2-DIPHENYL-2-OXOETHYLIDENEHYDRAZINO)-4-(4-METHOXYPHENYL)-4-OXOBUT-2-ENE ACID WITH ANTI-INFLAMMATORY AND ANALGESIC EFFECT 2006
  • Pulina Natal'Ja Alekseevna
  • Zalesov Vladimir Vasil'Evich
  • Bystritskaja Oksana Anatol'Evna
  • Jushkov Vladimir Viktorovich
  • Jatsenko Konstantin Vjacheslavovich
RU2348613C2
2-(4-BROMOPHENYLAMINO)-1-(PIPERAZIN-1-YL)-4-PHENYLBUT-2-EN-1,4-DIONE HYDROCHLORIDE HAVING INSECTICIDAL EFFECT 2015
  • Pulina Natalya Alekseevna
  • Kozhukhar Vyacheslav Yurevich
  • Syropyatov Boris Yakovlevich
  • Alikina Natalya Viktorovna
  • Rubtsov Aleksandr Evgenevich
RU2644162C2
2-HYDROXY-4-OXO-4-(4'-CHLOROPHENYL)-BUT-2-ENOAT 4-METHYL-2-PYRIDYLAMMONIUM THAT HAS A DIRECT ANTICOAGULANT ACTION 2015
  • Chernov Ilya Nikolaevich
  • Igidov Nazim Musabekovich
  • Syropyatov Boris Yakovlevich
  • Starkova Alla Valentinovna
  • Chashchina Svetlana Viktorovna
RU2649140C2

RU 2 663 624 C1

Authors

Pulina Natalya Alekseevna

Kuznetsov Aleksandr Sergeevich

Starkova Alla Valentinovna

Dates

2018-08-07Published

2016-07-11Filed