NOVEL IMIDAZOLIDINE-2,4-DIONE DERIVATIVES Russian patent published in 2018 - IPC C07D403/06 C07D401/14 A61K31/4166 A61P35/00 

Abstract RU 2655923 C2

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, namely to a heterocyclic compound of formula (I) wherein R1 is -CF3 group; R2 is (C1-C6)alkyl group; X is CH or N; R3 is a hydrogen atom or (C1-C6)alkyl group; R4 is (C1-C6)alkyl group; R5 is -CF3 group. Invention also relates to a pharmaceutical composition based on a compound of formula (I) and its use.

.

EFFECT: novel heterocyclic compounds useful in the treatment of cancer are obtained.

18 cl, 3 ex

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RU 2 655 923 C2

Authors

Oven Serzh

Lanko Kristof

Chao Tsi

Gu Kajchun

Dates

2018-05-30Published

2013-12-31Filed