REASSORTANT BTV AND AHSV VACCINES Russian patent published in 2018 - IPC A61K39/15 C12N15/86 

Abstract RU 2656187 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a vaccine for vaccinating animals, recombinant BTV (bluetongue virus) vector, a method for preparation thereof, a method for vaccinating an animal against BTV, and a method for producing an immunogenic or protective response in an animal against BTV. Described vaccine comprises a recombinant BTV vector comprising a heterologous polynucleotide encoding a BTV polypeptide, wherein the recombinant BTV vector comprises a vector base derived from a genome selected from the group consisting of serotypes 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25 and 26 BTV. Heterologous polynucleotide encodes an antigenic polypeptide from a BTV serotype that differs from the BTV serotype used as the vector backbone and is VP2.

EFFECT: inventions can be used to induce an immunogenic or protective response in animals against BTV.

25 cl, 18 dwg, 6 tbl, 4 ex

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RU 2 656 187 C2

Authors

Palmarini Massimo

Yudele Paskal

Odonne Zhan-Kristof

Nyun Sandro Filipe

Dates

2018-05-31Published

2013-06-13Filed