FIELD: chemistry.
SUBSTANCE: invention relates to production process of 4-(benzofuran-2-yl)butan-2-one derivatives of formula 1 a-j, comprising in the domino reaction of 2-hydroxybenzyl alcohols with 2-substituted furans in 1,2-dichloroethane in the presence of trifluoromethanesulfonic acid when heated.
.
EFFECT: obtained 4-(benzofuran-2-yl)butan-2-one 1a-j derivatives with yields of 75–97 % are of interest as starter compounds for the synthesis of substances for pharmaceutical use.
1 cl, 2 tbl, 10 ex
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