FIELD: chemistry.
SUBSTANCE: invention relates to the heterocyclic compounds synthesis - derivatives of (E)-4-(indol-2-yl)prop-2-en-1-one, which are of interest as the initial compounds for the pharmaceutical substances synthesis. The production method of (E)-4-(indol-2-yl)prop-2-en-1-one I derivatives involves in reaction of the available 2-(N-tosylamino) benzyl alcohols with 2-substituted furans with the reaction mixture further treatment with acetate palladium, para-benzoquinone and molecular iodine in the glacial acetic acid under heating.
Postal index.
EFFECT: increase of the yield.
2 tbl, 10 ex
Title | Year | Author | Number |
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RU2495027C1 |
METHOD FOR PREPARING 4-[1-(TOLYL-4-SULFONYL)-1H-INDOLYL-2]-BUT-3-ENE-2-ONE'S | 2005 |
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Authors
Dates
2017-10-23—Published
2016-12-14—Filed