FIELD: pharmacology.
SUBSTANCE: (E)-2-(2-acylvinyl)benzofuran derivatives of the formula I a-k
,
which are of interest as starting compounds for the synthesis of pharmaceutical substances, which consists in the reaction of 2-hydroxybenzyl alcohols with N-Tosyl furfurylamine in glacial acetic acid in the presence of stoichiometric amounts of hydrochloric acid at a temperature of 120°C.
.
EFFECT: improvement of the method.
2 tbl, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR OBTAINING DERIVATIVES OF 2-(2-ACYLVINYL)INDOLES | 2014 |
|
RU2570421C1 |
| PRODUCTION PROCESS OF 4-(BENZOFURAN-2-YL)BUTAN-2-ONE | 2017 |
|
RU2656208C1 |
| PRODUCTION METHOD OF (E)-4-(INDOL-2-YL)PROP-2-EN-1-ONE DERIVATIVES | 2016 |
|
RU2633999C1 |
| METHOD PRODUCING 4-{1-[(4-METHYLPHENYL)SULPHONYL]-1H-INDOL-2-YL}BUT-3-EN-2-ONE DERIVATIVES | 2012 |
|
RU2488581C1 |
| METHOD OF PRODUCING 2-(BENZYL)FURAN DERIVATIVES | 2014 |
|
RU2570420C1 |
| METHOD OF PRODUCING 4-(3,5-DIPHENYLFURAN-2-YL)BUTANONE-2 DERIVATIVES | 2016 |
|
RU2634000C1 |
| METHOD OF PRODUCING 2-(2-ACYLVINYL)INDOLES | 2012 |
|
RU2495027C1 |
| METHOD OF OBTAINING DERIVATIVES OF 2-ARYL(HETARYL)-1H-INDOLES | 2010 |
|
RU2439056C1 |
| METHOD FOR SYNTHESIS OF 4-(1H-INDOL-3-YL)-BUT-3-EN-2-ONE DERIVATIVES | 2009 |
|
RU2409564C1 |
| METHOD OF PRODUCING (E)-4-(6,7-DIMETHOXY-2-METHYL-3-QUINOLYL)-3-BUTEN-2-ONE DERIVATIVES | 2010 |
|
RU2425034C1 |
