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2 439 056

(13)

(51)

IPC

C07D209/08(2006-01-01)

C07D209/12(2006-01-01)

C07D405/04(2006-01-01)

C07D405/06(2006-01-01)

(21) (22)

Application

2010127792/04, 2010-07-05

(24)

Start date

2010-07-05

(22)

Actual filing date

2010-07-05

(45)

Published

2012-01-10

(72)

Inventor

Uchuskin Maksim Grigor'EvichPilipenko Arkadij SergeevichMolodtsova Natalija VladimirovnaButin Aleksandr Valerianovich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Tekhnologicheskij Universitet" Vpo

METHOD OF OBTAINING DERIVATIVES OF 2-ARYL(HETARYL)-1H-INDOLES Russian patent published in 2012 - IPC C07D209/08 C07D209/12 C07D405/04 C07D405/06

Abstract RU 2439056 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to method of obtaining derivatives of 2-aryl(hetaryl)-1H-indoles of general formula I:

Index R¹ R² Ia Cl Ib ОСН₃ Ic H Id H Ie Н If Cl Ig Cl

which is characterised by the fact that derivatives of 4-(1H-indol-3-yl)-but-3-en-2-ons II and phenylhydrazine hydrochloride are boiled in dimethylformamide for 2 min. Method ensures obtaining target products with output to 83%.

EFFECT: compounds can be used for synthesis of novel preparations of pharmaceutical purpose.

2 tbl, 10 ex

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RU 2 439 056 C1

Authors

Uchuskin Maksim Grigor'Evich

Pilipenko Arkadij Sergeevich

Molodtsova Natalija Vladimirovna

Butin Aleksandr Valerianovich

Dates

2012-01-10—Published

2010-07-05—Filed