PRODUCTION PROCESS OF 2-(FLUOROMETOXY)-1,1,1,3,3,3-HEXAFLUOROOPROPANE (SEVOFLURAN) Russian patent published in 2018 - IPC C07C41/22 C07C43/12 

Abstract RU 2656210 C1

FIELD: chemistry.

SUBSTANCE: present invention relates to production process of 2-(fluoromethoxy)-1,1,1,3,3,3-hexafluoroisopropane (sevoflurane), which is an inhalational anesthetic. Process consists in hydrofluorination of 2-(chloromethoxy)-1,1,1,3,3,3-hexafluoroisopropane (sevochlorane), which is performed with hydrofluoride in the presence of dimethylformamide at a temperature of 60–120 °C.

EFFECT: process according to the invention makes it possible to obtain the desired product in high yield, selectivity and a minimum amount of impurities using simple technology.

4 cl, 1 dwg, 3 tbl, 22 ex

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RU 2 656 210 C1

Authors

Barabanov Valerij Georgievich

Orlov Aleksandr Pavlovich

Kulya Tatyana Ivanovna

Shchavelev Vladimir Borisovich

Dates

2018-06-01Published

2017-10-17Filed