FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine and a topical composition comprising at least one alpha connexin polypeptide and hydroxyethylcellulose gel, wherein the hydroxyethylcellulose gel stabilizes the alpha connexin polypeptide, wherein the composition comprises the alpha connexin polypeptide at a concentration of about 0.0025 % (w/w) to about 5.00 % (w/w) and hydroxyethylcellulose at a concentration of about 0.5 % (w/w) to about 2.5 % (w/w). Group of inventions also relates to a method of wound treatment comprising administering the said composition to a subject in need thereof; method of manufacturing said composition.
EFFECT: group of inventions provides stability of the alpha-connexin polypeptide in the composition.
16 cl, 1 dwg, 2 ex, 9 tbl
