FIELD: medicine.
SUBSTANCE: group of inventions is based on discovery that Notch signal transduction pathway is connected with malignant tumour. In particular, group of inventions relate to ANTP/DN-MAML-including compositions, as well as to methods for treating malignant tumour by means of said compositions.
EFFECT: group of inventions makes it possible to treat malignant tumours, mediated by impairment of signal transduction in Notch pathway.
8 cl, 10 dwg, 2 tbl, 13 ex
| Title | Year | Author | Number |
|---|---|---|---|
| INHIBITORS OF NOTCH SIGNAL TRANSMISSION WAYS AND THEIR APPLICATION FOR CANCER TREATMENT | 2012 |
|
RU2631611C2 |
| IMPROVED STRATIFICATION OF PATIENTS TO EVALUATE THERAPY SUITABILITY | 2015 |
|
RU2711452C2 |
| COMPOSITIONS OF HUMANISED NOTCH FUSED PROTEINS AND METHODS OF TREATING | 2008 |
|
RU2532830C2 |
| USE OF microRNA BIOGENESIS IN EXOSOMES FOR DIAGNOSTICS AND TREATMENT | 2014 |
|
RU2644247C2 |
| HYBRID PROTEINS BASED ON HUMAN Notch3 AS TRAPS-INHIBITORS OF Notch3 SIGNAL TRANSMISSION | 2009 |
|
RU2567662C2 |
| NRR Notch1 ANTIBODIES AND METHODS OF APPLICATION THEREOF | 2008 |
|
RU2476443C2 |
| THERAPY OF INTESTINAL ADENOMA AND/OR ADENOCARCINOMA BY INHIBITING NOTCH ACTIVATION | 2005 |
|
RU2392961C2 |
| CHIMERIC PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER | 2010 |
|
RU2435783C1 |
| MARKERS ASSOCIATED WITH WNT INHIBITORS | 2014 |
|
RU2663701C2 |
| DIAGNOSTIC TECHNIQUE FOR BREAST CANCER | 2013 |
|
RU2547583C2 |
