FIELD: chemistry.
SUBSTANCE: invention relates to derivatives of 9-allylcamptothecin, including a compound of formula 14 as an essential intermediate for the preparation of a compound of formula 1 and its hydrochloride of formula 1H, which has an antitumor effect. Invention also relates to a process for the preparation of a compound of formula 14 and a process for the preparation of compounds 1 and 1H.
,
EFFECT: high overall yield of products.
10 cl, 8 ex
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