FIELD: chemistry.
SUBSTANCE: invention relates to 5-methoxy-2-(((4-methoxy-3-methyl-2-pyridinyl)methyl)sulfinyl)-6-methyl-3H-imidazo[4,5-b]pyridine or to its salt, as well as a pharmaceutical composition which inhibits secretion of gastric acid based on the said compound. Description is given of production of the new compound and a pharmaceutical composition based on the new compound, which can be used in medicine for treating such diseases as gastric ulcer, duodenal ulcer, stomal ulcer, gastroesophageal reflux, Zollinger-Ellison syndrome, symptomatic gastroesophageal reflux, endoscopy negative gastroesophageal reflux, gastroesophageal regurgitation, pharyngolaryngeal paresthesia, Barrett's esophagus, Non-steroidal anti-inflammatory drug (NSAID) induced ulcer, gastritis, gastric hemorrhage, gastrointestinal hemorrhage, peptic ulcer, bleeding ulcer, stress ulcer, gastric hyperchlorhydria, dyspepsia, gastroparesis, senile ulcer, intractable ulcer, heartburn, bruxism, stomach ache, heavy stomach or erosive gastritis.
EFFECT: increased effectiveness of composition and disease treatment.
7 cl, 6 tbl, 29 ex
| Title | Year | Author | Number |
|---|---|---|---|
| BENZIMIDAZOLE DERIVATIVE | 2006 |
|
RU2409573C2 |
| NOVEL COUMARIN DERIVATIVES WITH ANTI-TUMOUR ACTIVITY | 2007 |
|
RU2428420C2 |
| PYRAZOLE DERIVATIVE SUITABLE AS PI3K INHIBITOR | 2016 |
|
RU2710549C2 |
| PYRIDYLOXY DERIVATIVES EFFECTIVE AS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) GAMMA ACTIVATOR/MODULATOR | 2010 |
|
RU2480463C1 |
| BENZIMIDAZOLE DERIVATIVES, BASED PHARMACEUTICAL COMPOSITION AND METHODS OF USING THEM | 2008 |
|
RU2456276C2 |
| PRODRUG OF THE AMINO ACID DERIVATIVE | 2017 |
|
RU2739318C2 |
| INDAZOLIE WNT SIGNAL PATHWAY INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | 2017 |
|
RU2682245C1 |
| INDASOLE INHIBITORS OF Wnt SIGNAL PATH AND THEIR THERAPEUTIC APPLICATIONS | 2013 |
|
RU2638932C2 |
| 1H-PYRAZOLO[3,4-B]PYRIDINES AND THEIR THERAPEUTIC APPLICATIONS | 2013 |
|
RU2689141C2 |
| BICYCLIC IMIDAZOL DERIVATIVES AS MEDIUM AGAINST VIRUSES OF FLAVIVIRIDAE FAMILY | 2004 |
|
RU2355687C2 |
