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2 659 211

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IPC

G01N33/48(2006-01-01)

(21) (22)

Application

2016149602, 2016-12-16

(24)

Start date

2016-12-16

(22)

Actual filing date

2016-12-16

(45)

Published

2018-06-28

(72)

Inventor

Orekhov Aleksandr NikolaevichSobenin Igor AleksandrovichMelnichenko Aleksandra AleksandrovnaOrekhova Natalya MikhajlovnaSukhorukov Vasilij NikolaevichVoropaeva Nadezhda PetrovnaPolunina Lyudmila IvanovnaRomanenko Elena BorisovnaKaragodin Vasilij Petrovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Institut Obshchej Patologii I Patofiziologii"

METHOD FOR MEASURING THE CONCENTRATION OF CIRCULATING MODIFIED LOW-DENSITY LIPOPROTEINS IN HUMAN BLOOD SERUM Russian patent published in 2018 - IPC G01N33/48

Abstract RU 2659211 C2

FIELD: medicine.

SUBSTANCE: invention relates to medicine and clinical biochemistry and can be used in laboratory diagnostics for determining circulating modified low-density lipoproteins (cmLDL) for diagnostic and therapeutic purposes. Method for quantitatively determining the content of circulating modified low-density lipoproteins in blood of patients comprises measuring the level of desialylate apoprotein B-100 by enzyme multipled immunoassay with the use of ricin agglutinin PKA 120, which binds to terminal galactose in desialylate apoprotein B-100.

EFFECT: proposed is a method for quantitatively determining the content of circulating modified low-density lipoproteins in blood.

1 cl, 2 ex

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RU 2 659 211 C2

Authors

Orekhov Aleksandr Nikolaevich

Sobenin Igor Aleksandrovich

Melnichenko Aleksandra Aleksandrovna

Orekhova Natalya Mikhajlovna

Sukhorukov Vasilij Nikolaevich

Voropaeva Nadezhda Petrovna

Polunina Lyudmila Ivanovna

Romanenko Elena Borisovna

Karagodin Vasilij Petrovich

Dates

2018-06-28—Published

2016-12-16—Filed